SKF 525A (hydrochloride) (CAS 62 68 0) Cayman Chemical

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Proadifen - Wikiped

Proadifen (SKF-525A) is a non-selective inhibitor of cytochrome P450 enzymes, preventing some types of drug metabolism. It is also an inhibitor of neuronal nitric oxide synthase (NOS), CYP-dependent (cytochrome P450-dependent) arachidonate metabolism, transmembrane calcium influx, and platelet thromboxane synthesis.

Proadifen Hydrochloride, =95% - Thomas S

Proadifen Hydrochloride, =95% from Thomassci.com, your source for Laboratory Equipment and Scientific Supplies

CAS # 62-68-0 | Proadifen Hydrochloride Spectrum-Chemical .

Spectrum Chemical manufactures and distributes fine chemicals with quality you can count on including those with CAS number 62-68-0, Whether you call it Proadifen Hydrochloride, 2-[Diethylamino]ethyl Ester Hydrochloride , alpha-Phenyl-alpha-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester Hydrochloride or SKF-525A Hydrochloride you can be assured the Proadifen Hydrochloride products ...

SKF525A HCl Supplier | CAS 62-68-0 | Focus Biomolecul

SKF-525A (62-68-0) is a commonly used non-selective Cytochrome P450 inhibitor. 1 It is also a local anesthetic 2 acting via blockage of the acetylcholine receptor 3 – it is a commonly used reagent to stabilize the desensitized state of muscle AChR 4.SKF-525A also inhibits glibenclamide-sensitive K + channels. 5. References/Citations

62-68-0 - Proadifen hydrochloride - SKF-525A hydrochloride .

Proadifen hydrochloride is an inhibitor of NOS1, AChR, cytochrome P-450, and KIR6. Proadifen hydrochloride bind to the protein moiety of P-450, also reduced the hypoxic response. of Proadifen hydrochloride have good antiarrhythmic effects. SKF-525A substantially reduced the depletion of cardiac norepinephrine.

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SKF 525A (hydrochloride) - C23H31NO2 • HCl - Bertin Bioreage

A widely used, nonspecific CYP450 inhibitor that potentiates the effects of many different different drugs by inhibiting their metabolism (IC50 values in the μM ...

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52.193995381062351 226. 9.006928406466514 39. 5.0808314087759809 22. 5.0808314087759809 22. 4.8498845265588919 21. 4.1570438799076213 18. 3.695150115473441 16. 2 ...


This nonselective P450 inhibitor (FWfree-base = 353.50 g/mol; CAS 302-33-0; 62-68-0 for the HCl salt), also known as SKF-525A, b-diethylaminoethyl 2,2-diphenylpropylacetate, and N,N-diethylaminoethyl 2,2- diphenylvalerate, blocks glibenclamide-sensitive K+ channels, including ATP-sensitive inward rectifier potassium channel 8 (KIR6.1).

SKF 525A (hydrochloride) (CAS 62-68-0) | Cayman Chemic

SKF 525A is a widely used, nonspecific cytochrome P (CYP)450 inhibitor that demonstrates 100% inhibition of the various CYP450 isoforms at 1-100 μM. 1 It therefore potentiates the effects of many different drugs by inhibiting their metabolism (IC 50 values in the μM range when tested using human liver microsomes). 2 SKF 525A inhibits CYP450 ...


Visit ChemicalBook To find more PROADIFEN HYDROCHLORIDE(62-68-0) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. You can also browse global suppliers,vendor,prices,Price,manufacturers of PROADIFEN HYDROCHLORIDE(62-68-0).

Proadifen hydrochloride | C23H32ClNO2 - PubCh

Proadifen hydrochloride. 62-68-0. Proadifen HCl. Propyladiphenin. SKF-525A hydrochloride. SKF 525A. Proadifen (hydrochloride) SK&F 525-A. RP 5171. SKF-525A. Proadifen hydrochloride [USAN] UNII-30624AA6X2. SKF 525-A. NSC 39690. U 5446. NSC 170997. SKF-525A, Hydrochloride. 5171 RP. 2-Diethylaminoethyl 2,2-diphenylvalerate hydrochloride


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SKF-525A, Hydrochloride (Proadifen) - Thomas S

SKF-525A, Hydrochloride (Proadifen) from Thomassci.com, your source for Laboratory Equipment and Scientific Supplies

CAS No. 62-68-0 | Sigma-Aldri

Search results for 62-68-0 at Sigma-Aldrich. Attention: As part of planned maintenance, many Safety Data Sheets (SDS) will be unavailable on Sunday, July 14, 2019 from 10:55am CDT to 2pm CDT.

5-hydroxytryptamine has an endothelium-derived .

5-hydroxytryptamine (5-HT)-induced coronary artery responses have both vasoconstriction and vasorelaxation components. The vasoconstrictive effects of 5-HT have been well studied while the mechanism(s) of how 5-HT causes relaxation of coronary arteries has been less investigated. In isolated rat hearts, 5-HT-induced coronary flow increases are partially resistant to the nitric oxide synthase ...

SKF 525A Hydrochloride | Spectrum Chemic

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SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem | Sigma .

SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem Cell permeable. Blocks glibenclamide-sensitive K + channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system. Synonym: Proadifen, Proadifen CAS Number 62-68-0. Empirical Formula (Hill Notation) C 23 H 31 NO 2 · xHCl